In 2017, Dr.Li Chen founded Likang Life Sciences with a focus on the research, development, and commercialization of precision immunotherapies for cancer. Under his leadership, the company’s leading product, LK-101, received clinical trial clearance from China’s National Medical Products Administration (NMPA) in 2023 and successfully entered Phase I clinical development, becoming the first AI-driven, personalized mRNA cancer vaccine targeting patient-specific tumor antigens to advance into clinical trials in China. In 2025, LK-101 also received clinical trial clearance from the U.S. Food and Drug Administration (FDA), making it the first—and currently the only—China-developed product of its kind authorized to enter clinical trials in the United States.
Beyond advancing clinical development in both China and the United States, LK-101 has also achieved a significant milestone in translating technological innovation into real-world application. As the world’s first AI-driven, personalized mRNA cancer vaccine of its kind approved for commercial use, LK-101 has been applied in more than 100 cases since receiving approval in Hainan in February 2025, covering 10 types of solid tumors, including lung, pancreatic, and liver cancers.
Dr.Li Chen was selected for the Beijing Association for Science and Technology’s Young Talent Development Program in 2022. In 2023, he was named to the MIT Technology Review Innovators Under 35 Asia Pacific list and recognized by 36Kr as an “X·36Under36” S-tier young entrepreneur. In 2026, he received the Forbes China Industry Development Leadership Award.
2017年,陈立博士创立了立康生命科技,专注于肿瘤精准免疫治疗药物的研发与产业化。在其带领下,公司自主研发的核心产品LK-101于2023年获得中国国家药品监督管理局(NMPA)临床试验许可,并顺利进入Ⅰ期临床研究,成为国内首款获准进入临床阶段的AI驱动个性化靶点mRNA肿瘤疫苗。2025年,LK-101进一步获得美国食品药品监督管理局(FDA)临床试验许可,成为中国首个且目前唯一获准在美国开展临床试验的同类产品。
除推进中美临床开发外,LK-101还率先实现了从技术研发到转化应用的跨越。作为全球首款获准商业化应用的AI驱动个性化靶点mRNA肿瘤疫苗,LK-101自2025年2月在海南获批应用以来,已完成上百例转化应用,覆盖肺癌、胰腺癌、肝癌等10类实体瘤。
陈立博士于2022年入选北京市科学技术协会“青年人才托举工程”;2023年入选《麻省理工科技评论》亚太区“35岁以下科技创新35人”,并获评36氪“X·36Under36”S级青年创业者;2026年荣获“福布斯中国行业发展领创者”称号。